2oo5: Difference between revisions

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[[Image:2oo5.gif|left|200px]]<br /><applet load="2oo5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2oo5.gif|left|200px]]
caption="2oo5, resolution 2.600&Aring;" />
 
'''Structure of transhydrogenase (dI.H2NADH)2(dIII.NADP+)1 asymmetric complex'''<br />
{{Structure
|PDB= 2oo5 |SIZE=350|CAPTION= <scene name='initialview01'>2oo5</scene>, resolution 2.600&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=TXD:1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE'>TXD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/NAD(P)(+)_transhydrogenase_(AB-specific) NAD(P)(+) transhydrogenase (AB-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.1.2 1.6.1.2]
|GENE= pntAA, nntA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1085 Rhodospirillum rubrum]), pntB, nntB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1085 Rhodospirillum rubrum])
}}
 
'''Structure of transhydrogenase (dI.H2NADH)2(dIII.NADP+)1 asymmetric complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OO5 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rhodospirillum_rubrum Rhodospirillum rubrum] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=TXD:'>TXD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/NAD(P)(+)_transhydrogenase_(AB-specific) NAD(P)(+) transhydrogenase (AB-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.1.2 1.6.1.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OO5 OCA].  
2OO5 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rhodospirillum_rubrum Rhodospirillum rubrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OO5 OCA].  


==Reference==
==Reference==
Structures of the dI2dIII1 complex of proton-translocating transhydrogenase with bound, inactive analogues of NADH and NADPH reveal active site geometries., Bhakta T, Whitehead SJ, Snaith JS, Dafforn TR, Wilkie J, Rajesh S, White SA, Jackson JB, Biochemistry. 2007 Mar 20;46(11):3304-18. Epub 2007 Feb 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17323922 17323922]
Structures of the dI2dIII1 complex of proton-translocating transhydrogenase with bound, inactive analogues of NADH and NADPH reveal active site geometries., Bhakta T, Whitehead SJ, Snaith JS, Dafforn TR, Wilkie J, Rajesh S, White SA, Jackson JB, Biochemistry. 2007 Mar 20;46(11):3304-18. Epub 2007 Feb 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17323922 17323922]
[[Category: NAD(P)(+) transhydrogenase (AB-specific)]]
[[Category: NAD(P)(+) transhydrogenase (AB-specific)]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: rossmann fold; nad(h)-binding site; nadp(h)-binding site]]
[[Category: rossmann fold; nad(h)-binding site; nadp(h)-binding site]]


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