4u7d: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Structure of human RECQ-like helicase in complex with an oligonucleotide==

~~The entry~~ 4u7d is ~~ON HOLD~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4u7d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U7D OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U7D FirstGlance].

~~Authors~~: ~~Pike~~, A.C.W.~~, Zhang, Y~~.~~, Schnecke, C~~., ~~Cooper, C~~.D.O., ~~Von Delft, F~~.~~, Arrowsmith, C~~.H., ~~Edwards, A~~.~~, Bountra, C~~.~~, Gileadi, O~~.~~, Structural Genomics Consortium (SGC)~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </td></tr>

~~Description~~: ~~Structure~~ of ~~human RECQ~~-~~like~~ helicase in ~~complex with an oligonucleotide~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u7d RCSB], [http://www.ebi.ac.uk/pdbsum/4u7d PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

[[Category: ~~Pike~~, A.C~~.W]]~~

== Function ==

~~[[Category: Zhang, Y~~]]

[[http://www.uniprot.org/uniprot/RECQ1_HUMAN RECQ1_HUMAN]] DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.<ref>PMID:15886194</ref> <ref>PMID:7961977</ref> <ref>PMID:8056767</ref>

== References ==

__TOC__

</StructureSection>

[[Category: DNA helicase]]

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C]]

[[Category: Cooper, C D.O]]

[[Category: Delft, F Von]]

[[Category: Edwards, A]]

[[Category: Gileadi, O]]

[[Category: Pike, A C.W]]

[[Category: Structural genomic]]

[[Category: Schnecke, C]]

[[Category: ~~Arrowsmith~~, ~~C.H~~]]

[[Category: Zhang, Y]]

[[Category: ~~Von Delft, F~~]]

[[Category: Dna binding protein]]

[[Category: ~~Gileadi, O~~]]

[[Category: Dna strand annealing]]

[[Category: ~~Structural Genomics Consortium (Sgc)~~]]

[[Category: Hydrolase]]

[[Category: ~~Edwards, A~~]]

[[Category: Hydrolase-dna complex]]

[[Category: ~~Cooper, C.D.O~~]]

[[Category: Nuclear protein]]

[[Category: Sgc]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Structure of human RECQ-like helicase in complex with an oligonucleotide==
+<StructureSection load='4u7d' size='340' side='right' caption='[[4u7d]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
-The entry 4u7d is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4u7d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U7D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U7D FirstGlance]. <br>
-Authors: Pike, A.C.W., Zhang, Y., Schnecke, C., Cooper, C.D.O., Von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O., Structural Genomics Consortium (SGC)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
-Description: Structure of human RECQ-like helicase in complex with an oligonucleotide
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u7d RCSB], [http://www.ebi.ac.uk/pdbsum/4u7d PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Pike, A.C.W]]
+== Function ==
-[[Category: Zhang, Y]]
+[[http://www.uniprot.org/uniprot/RECQ1_HUMAN RECQ1_HUMAN]] DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.<ref>PMID:15886194</ref> <ref>PMID:7961977</ref> <ref>PMID:8056767</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: DNA helicase]]
+[[Category: Arrowsmith, C H]]
 [[Category: Bountra, C]]
+[[Category: Cooper, C D.O]]
+[[Category: Delft, F Von]]
+[[Category: Edwards, A]]
+[[Category: Gileadi, O]]
+[[Category: Pike, A C.W]]
+[[Category: Structural genomic]]
 [[Category: Schnecke, C]]
-[[Category: Arrowsmith, C.H]]
+[[Category: Zhang, Y]]
-[[Category: Von Delft, F]]
+[[Category: Dna binding protein]]
-[[Category: Gileadi, O]]
+[[Category: Dna strand annealing]]
-[[Category: Structural Genomics Consortium (Sgc)]]
+[[Category: Hydrolase]]
-[[Category: Edwards, A]]
+[[Category: Hydrolase-dna complex]]
-[[Category: Cooper, C.D.O]]
+[[Category: Nuclear protein]]
+[[Category: Sgc]]