2kw3

Heterotrimeric interaction between RFX5 and RFXAP

spinqualitylabelsall models 2kw3, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2kw3 is a 3 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: RFX5 (Homo sapiens), RFXAP (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Disease [RFX5_HUMAN] Immunodeficiency by defective expression of HLA class 2. The disease is caused by mutations affecting the gene represented in this entry. [RFXAP_HUMAN] Immunodeficiency by defective expression of HLA class 2. The disease is caused by mutations affecting the gene represented in this entry. Function [RFX5_HUMAN] Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters. [RFXAP_HUMAN] Part of the RFX complex that binds to the X-box of MHC II promoters. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Proteopedia Page Contributors and Editors (what is this?)

OCA