2oyq: Difference between revisions

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[[Image:2oyq.gif|left|200px]]<br /><applet load="2oyq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2oyq.gif|left|200px]]
caption="2oyq, resolution 2.86&Aring;" />
 
'''Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog'''<br />
{{Structure
|PDB= 2oyq |SIZE=350|CAPTION= <scene name='initialview01'>2oyq</scene>, resolution 2.86&Aring;
|SITE= <scene name='pdbsite=AC1:3dr+Binding+Site+For+Residue+E+6'>AC1</scene>, <scene name='pdbsite=AC2:N5i+Binding+Site+For+Residue+F+115'>AC2</scene>, <scene name='pdbsite=AC3:3dr+Binding+Site+For+Residue+I+6'>AC3</scene>, <scene name='pdbsite=AC4:N5i+Binding+Site+For+Residue+J+115'>AC4</scene>, <scene name='pdbsite=AC5:Mg+Binding+Site+For+Residue+I+802'>AC5</scene>, <scene name='pdbsite=AC6:N5p+Binding+Site+For+Residue+C+904'>AC6</scene>, <scene name='pdbsite=AC7:N5p+Binding+Site+For+Residue+A+904'>AC7</scene>, <scene name='pdbsite=AC8:N5p+Binding+Site+For+Residue+A+905'>AC8</scene> and <scene name='pdbsite=AC9:N5p+Binding+Site+For+Residue+I+704'>AC9</scene>
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=N5P:1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO-1H-INDOLE'>N5P</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7]
|GENE= 43 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12353 Enterobacteria phage RB69])
}}
 
'''Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OYQ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=N5P:'>N5P</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYQ OCA].  
2OYQ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYQ OCA].  


==Reference==
==Reference==
Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide., Zahn KE, Belrhali H, Wallace SS, Doublie S, Biochemistry. 2007 Sep 18;46(37):10551-61. Epub 2007 Aug 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17718515 17718515]
Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide., Zahn KE, Belrhali H, Wallace SS, Doublie S, Biochemistry. 2007 Sep 18;46(37):10551-61. Epub 2007 Aug 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17718515 17718515]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Enterobacteria phage rb69]]
[[Category: Enterobacteria phage rb69]]
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[[Category: transferase/dna complex]]
[[Category: transferase/dna complex]]


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