Magainin 2: Difference between revisions
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==Crystalization of Ala-Magainin== | ==Crystalization of Ala-Magainin== | ||
So far we had shown Magainin 2 structure based only on NMR findings, since it is | So far we had shown Magainin 2 structure based only on NMR findings, Because helical AMPs crystallography is limited, since it is hard to form crystals. | ||
In the Hypuka et al., 2013, In order to perform crystallization of Magainin 2, changes in the sequence were maid, and Ala-Magainin 2 was contsructed. In Ala-magainin one Ser (S) and two Gly (G) residues have been changed to Ala (A) in order to increase helical propensity. | |||