2p6g: Difference between revisions

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[[Image:2p6g.jpg|left|200px]]<br /><applet load="2p6g" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2p6g.jpg|left|200px]]
caption="2p6g, resolution 3.000&Aring;" />
 
'''Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors'''<br />
{{Structure
|PDB= 2p6g |SIZE=350|CAPTION= <scene name='initialview01'>2p6g</scene>, resolution 3.000&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene> and <scene name='pdbligand=3LP:1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL'>3LP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97]
|GENE= 850892 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2P6G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=MYA:'>MYA</scene> and <scene name='pdbligand=3LP:'>3LP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P6G OCA].  
2P6G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P6G OCA].  


==Reference==
==Reference==
Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region., Wu J, Tao Y, Zhang M, Howard MH, Gutteridge S, Ding J, J Biol Chem. 2007 Jul 27;282(30):22185-94. Epub 2007 May 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17513302 17513302]
Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region., Wu J, Tao Y, Zhang M, Howard MH, Gutteridge S, Ding J, J Biol Chem. 2007 Jul 27;282(30):22185-94. Epub 2007 May 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17513302 17513302]
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: non-peptidic inhibitor]]
[[Category: non-peptidic inhibitor]]


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