2p7f: Difference between revisions
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[[Image:2p7f.gif|left|200px]] | [[Image:2p7f.gif|left|200px]] | ||
'''The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme''' | {{Structure | ||
|PDB= 2p7f |SIZE=350|CAPTION= <scene name='initialview01'>2p7f</scene>, resolution 2.35Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=NCO:COBALT HEXAMMINE ION'>NCO</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2P7F is a [ | 2P7F is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7F OCA]. | ||
==Reference== | ==Reference== | ||
A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization., Torelli AT, Krucinska J, Wedekind JE, RNA. 2007 Jul;13(7):1052-70. Epub 2007 May 8. PMID:[http:// | A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization., Torelli AT, Krucinska J, Wedekind JE, RNA. 2007 Jul;13(7):1052-70. Epub 2007 May 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17488874 17488874] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Krucinska, J.]] | [[Category: Krucinska, J.]] | ||
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[[Category: SO4]] | [[Category: SO4]] | ||
[[Category: 5' phosphodiester; vanadate; reaction intermediate; transition-state stabilization; active site waters; induced fit]] | [[Category: 5' phosphodiester; vanadate; reaction intermediate; transition-state stabilization; active site waters; induced fit]] | ||
[[Category: hairpin ribozyme; | [[Category: hairpin ribozyme; 2s']] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:09:40 2008'' | ||