2p8u: Difference between revisions
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[[Image:2p8u.gif|left|200px]] | [[Image:2p8u.gif|left|200px]] | ||
'''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I''' | {{Structure | ||
|PDB= 2p8u |SIZE=350|CAPTION= <scene name='initialview01'>2p8u</scene>, resolution 2.00Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10] | |||
|GENE= HMGCS1, HMGCS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I''' | |||
==Disease== | ==Disease== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
2P8U is a [ | 2P8U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8U OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hydroxymethylglutaryl-CoA synthase]] | [[Category: Hydroxymethylglutaryl-CoA synthase]] | ||
| Line 33: | Line 42: | ||
[[Category: mevalonate pathway]] | [[Category: mevalonate pathway]] | ||
[[Category: sgc]] | [[Category: sgc]] | ||
[[Category: structural | [[Category: structural genomic]] | ||
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:10:13 2008'' | ||
Revision as of 16:10, 20 March 2008
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| 2p8u, resolution 2.00Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | COA and GOL | ||||||||||||
| Gene: | HMGCS1, HMGCS (Homo sapiens) | ||||||||||||
| Activity: | Hydroxymethylglutaryl-CoA synthase, with EC number 2.3.3.10 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I
Disease
Known disease associated with this structure: HMG-CoA synthase-2 deficiency OMIM:[600234]
About this Structure
2P8U is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:10:13 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Hydroxymethylglutaryl-CoA synthase
- Single protein
- Arrowsmith, C H.
- Bunkoczi, G.
- Burgess, N.
- Debreczeni, J.
- Delft, F von.
- Edwards, A.
- Gorrec, F.
- Niesen, F H.
- Oppermann, U.
- Pike, A C.W.
- SGC, Structural Genomics Consortium.
- Salah, E.
- Shafqat, N.
- Sundstrom, M.
- Turnbull, A P.
- Umeano, C.
- Weigelt, J.
- COA
- GOL
- Hydromethylglutaryl coa
- Mevalonate pathway
- Sgc
- Structural genomic
- Structural genomics consortium
