4oud: Difference between revisions
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''' | ==Engineered tyrosyl-tRNA synthetase with the nonstandard amino acid L-4,4-biphenylalanine== | ||
<StructureSection load='4oud' size='340' side='right' caption='[[4oud]], [[Resolution|resolution]] 2.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4oud]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OUD FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr> | |||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BIF:(R)-2-AMINO-3-(4-PHENYLCYCLOHEXYL)PROPANOIC+ACID'>BIF</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oud RCSB], [http://www.ebi.ac.uk/pdbsum/4oud PDBsum]</span></td></tr> | ||
[[Category: Church, G | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/U6N9P2_ECOLI U6N9P2_ECOLI]] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02006][SAAS:SAAS00105801] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Tyrosine--tRNA ligase]] | |||
[[Category: Church, G M]] | |||
[[Category: Lajoie, M J]] | |||
[[Category: Mandell, D J]] | |||
[[Category: Stoddard, B L]] | |||
[[Category: Takeuchi, R]] | [[Category: Takeuchi, R]] | ||
[[Category: | [[Category: Complex with l-tyrosine]] | ||
[[Category: | [[Category: Ligase]] | ||
[[Category: | [[Category: Rossmann fold]] | ||
[[Category: Trna]] | |||
Revision as of 16:45, 28 January 2015
Engineered tyrosyl-tRNA synthetase with the nonstandard amino acid L-4,4-biphenylalanine
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