3wsy: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==SorLA Vps10p domain in complex with its own propeptide fragment==

~~The entry~~ 3wsy is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[3wsy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSY OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WSY FirstGlance].

~~Authors~~: ~~Kitago~~, Y., ~~Nakata~~, Z., ~~Nagae~~, M., ~~Nogi~~, T.~~, Takagi, J~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3wsx|3wsx]], [[3wsz|3wsz]]</td></tr>

~~Description~~: ~~Neuronal extracellular receptor N-term domain with the ligand peptide~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wsy RCSB], [http://www.ebi.ac.uk/pdbsum/3wsy PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/SORL_HUMAN SORL_HUMAN]] Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction.

__TOC__

</StructureSection>

[[Category: Kitago, Y]]

[[Category: Nagae, M]]

[[Category: Nakata, Z]]

[[Category: Nogi, T]]

[[Category: Takagi, J]]

[[Category: ~~Nakata, Z~~]]

[[Category: Beta-propeller]]

[[Category: ~~Nagae, M~~]]

[[Category: Protein binding]]

[[Category: ~~Kitago, Y~~]]

[[Category: Receptor]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==SorLA Vps10p domain in complex with its own propeptide fragment==
+<StructureSection load='3wsy' size='340' side='right' caption='[[3wsy]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
-The entry 3wsy is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3wsy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WSY FirstGlance]. <br>
-Authors: Kitago, Y., Nakata, Z., Nagae, M., Nogi, T., Takagi, J.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wsx|3wsx]], [[3wsz|3wsz]]</td></tr>
-Description: Neuronal extracellular receptor N-term domain with the ligand peptide
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wsy RCSB], [http://www.ebi.ac.uk/pdbsum/3wsy PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/SORL_HUMAN SORL_HUMAN]] Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction.
+__TOC__
+</StructureSection>
+[[Category: Kitago, Y]]
+[[Category: Nagae, M]]
+[[Category: Nakata, Z]]
 [[Category: Nogi, T]]
 [[Category: Takagi, J]]
-[[Category: Nakata, Z]]
+[[Category: Beta-propeller]]
-[[Category: Nagae, M]]
+[[Category: Protein binding]]
-[[Category: Kitago, Y]]
+[[Category: Receptor]]