2pqd: Difference between revisions

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New page: left|200px<br /><applet load="2pqd" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pqd, resolution 1.770Å" /> '''A100G CP4 EPSPS lig...
 
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[[Image:2pqd.jpg|left|200px]]<br /><applet load="2pqd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pqd.jpg|left|200px]]
caption="2pqd, resolution 1.770&Aring;" />
 
'''A100G CP4 EPSPS liganded with (R)-difluoromethyl tetrahedral reaction intermediate analog'''<br />
{{Structure
|PDB= 2pqd |SIZE=350|CAPTION= <scene name='initialview01'>2pqd</scene>, resolution 1.770&Aring;
|SITE= <scene name='pdbsite=AC1:Gg9+Binding+Site+For+Residue+A+501'>AC1</scene>
|LIGAND= <scene name='pdbligand=GG9:'>GG9</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-phosphoshikimate_1-carboxyvinyltransferase 3-phosphoshikimate 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.19 2.5.1.19]
|GENE= aroA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=361 Agrobacterium sp.])
}}
 
'''A100G CP4 EPSPS liganded with (R)-difluoromethyl tetrahedral reaction intermediate analog'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PQD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.] with <scene name='pdbligand=GG9:'>GG9</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/3-phosphoshikimate_1-carboxyvinyltransferase 3-phosphoshikimate 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.19 2.5.1.19] Known structural/functional Site: <scene name='pdbsite=AC1:Gg9+Binding+Site+For+Residue+A+501'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQD OCA].  
2PQD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQD OCA].  


==Reference==
==Reference==
Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues., Funke T, Healy-Fried ML, Han H, Alberg DG, Bartlett PA, Schonbrunn E, Biochemistry. 2007 Nov 20;46(46):13344-51. Epub 2007 Oct 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17958399 17958399]
Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues., Funke T, Healy-Fried ML, Han H, Alberg DG, Bartlett PA, Schonbrunn E, Biochemistry. 2007 Nov 20;46(46):13344-51. Epub 2007 Oct 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17958399 17958399]
[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
[[Category: Agrobacterium sp.]]
[[Category: Agrobacterium sp.]]
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[[Category: transferase]]
[[Category: transferase]]


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