2ps1: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:2ps1.jpg|left|200px]]<br /><applet load="2ps1" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ps1.jpg|left|200px]]
caption="2ps1, resolution 1.750&Aring;" />
 
'''S. cerevisiae orotate phosphoribosyltransferase complexed with orotic acid and PRPP'''<br />
{{Structure
|PDB= 2ps1 |SIZE=350|CAPTION= <scene name='initialview01'>2ps1</scene>, resolution 1.750&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene> and <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID'>PRP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10]
|GENE= URA5, PYR5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''S. cerevisiae orotate phosphoribosyltransferase complexed with orotic acid and PRPP'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
2PS1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ORO:'>ORO</scene> and <scene name='pdbligand=PRP:'>PRP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS1 OCA].  
2PS1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS1 OCA].  


==Reference==
==Reference==
Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase., Gonzalez-Segura L, Witte JF, McClard RW, Hurley TD, Biochemistry. 2007 Dec 11;46(49):14075-86. Epub 2007 Nov 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18020427 18020427]
Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase., Gonzalez-Segura L, Witte JF, McClard RW, Hurley TD, Biochemistry. 2007 Dec 11;46(49):14075-86. Epub 2007 Nov 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18020427 18020427]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
Line 24: Line 33:
[[Category: transferase]]
[[Category: transferase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:32:26 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:16:41 2008''
Retrieved from "https://proteopedia.org/2ps1"