2pw3: Difference between revisions

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[[Image:2pw3.gif|left|200px]]<br /><applet load="2pw3" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pw3.gif|left|200px]]
caption="2pw3, resolution 1.56&Aring;" />
 
'''Structure of the PDE4D-cAMP complex'''<br />
{{Structure
|PDB= 2pw3 |SIZE=350|CAPTION= <scene name='initialview01'>2pw3</scene>, resolution 1.56&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CMP:ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE'>CMP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17]
|GENE= PDE4D ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of the PDE4D-cAMP complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PW3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=CMP:'>CMP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PW3 OCA].  
2PW3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PW3 OCA].  


==Reference==
==Reference==
The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10., Wang H, Robinson H, Ke H, J Mol Biol. 2007 Aug 10;371(2):302-7. Epub 2007 May 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17582435 17582435]
The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10., Wang H, Robinson H, Ke H, J Mol Biol. 2007 Aug 10;371(2):302-7. Epub 2007 May 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17582435 17582435]
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: substrate specificity]]
[[Category: substrate specificity]]


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