4woh: Difference between revisions
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==Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate== | |||
<StructureSection load='4woh' size='340' side='right' caption='[[4woh]], [[Resolution|resolution]] 1.34Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4woh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WOH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NP:4-NITROPHENYL+PHOSPHATE'>4NP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4woh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4woh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4woh RCSB], [http://www.ebi.ac.uk/pdbsum/4woh PDBsum]</span></td></tr> | |||
</table> | |||
[[ | == Function == | ||
[[ | [[http://www.uniprot.org/uniprot/DUS22_HUMAN DUS22_HUMAN]] Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).<ref>PMID:11717427</ref> | ||
[[ | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Cherry, S]] | [[Category: Cherry, S]] | ||
[[Category: Lountos, G | [[Category: Lountos, G T]] | ||
[[Category: Tropea, J E]] | |||
[[Category: Waugh, D S]] | |||
[[Category: Dual specificity phosphatase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Jsp-1]] | |||
[[Category: Pnpp]] | |||
Revision as of 13:11, 18 February 2015
Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate
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