2q5j: Difference between revisions

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[[Image:2q5j.jpg|left|200px]]<br /><applet load="2q5j" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q5j.jpg|left|200px]]
caption="2q5j, resolution 3.20&Aring;" />
 
'''X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP'''<br />
{{Structure
|PDB= 2q5j |SIZE=350|CAPTION= <scene name='initialview01'>2q5j</scene>, resolution 3.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=TPW:2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE'>TPW</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylpyruvate_decarboxylase Phenylpyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.43 4.1.1.43]
|GENE= ipdC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192 Azospirillum brasilense])
}}
 
'''X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q5J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Azospirillum_brasilense Azospirillum brasilense] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=TPW:'>TPW</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phenylpyruvate_decarboxylase Phenylpyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.43 4.1.1.43] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q5J OCA].  
2Q5J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Azospirillum_brasilense Azospirillum brasilense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q5J OCA].  


==Reference==
==Reference==
Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase., Versees W, Spaepen S, Wood MD, Leeper FJ, Vanderleyden J, Steyaert J, J Biol Chem. 2007 Nov 30;282(48):35269-78. Epub 2007 Sep 28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17905741 17905741]
Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase., Versees W, Spaepen S, Wood MD, Leeper FJ, Vanderleyden J, Steyaert J, J Biol Chem. 2007 Nov 30;282(48):35269-78. Epub 2007 Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17905741 17905741]
[[Category: Azospirillum brasilense]]
[[Category: Azospirillum brasilense]]
[[Category: Phenylpyruvate decarboxylase]]
[[Category: Phenylpyruvate decarboxylase]]
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[[Category: MG]]
[[Category: MG]]
[[Category: TPW]]
[[Category: TPW]]
[[Category: asymmetric dimer of dimers]]
[[Category: asymmetric dimer of dimer]]
[[Category: cofactor analogue]]
[[Category: cofactor analogue]]
[[Category: lyase]]
[[Category: lyase]]
[[Category: open active site loops]]
[[Category: open active site loop]]
[[Category: thiamine diphosphate]]
[[Category: thiamine diphosphate]]


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