2q5q: Difference between revisions

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[[Image:2q5q.jpg|left|200px]]<br /><applet load="2q5q" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q5q.jpg|left|200px]]
caption="2q5q, resolution 1.90&Aring;" />
 
'''X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP and 5-phenyl-2-oxo-valeric acid'''<br />
{{Structure
|PDB= 2q5q |SIZE=350|CAPTION= <scene name='initialview01'>2q5q</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPW:2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPW</scene>, <scene name='pdbligand=KPV:5-PHENYL-2-KETO-VALERIC+ACID'>KPV</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylpyruvate_decarboxylase Phenylpyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.43 4.1.1.43]
|GENE= ipdC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192 Azospirillum brasilense])
}}
 
'''X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP and 5-phenyl-2-oxo-valeric acid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q5Q is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Azospirillum_brasilense Azospirillum brasilense] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=TPW:'>TPW</scene>, <scene name='pdbligand=KPV:'>KPV</scene>, <scene name='pdbligand=TLA:'>TLA</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phenylpyruvate_decarboxylase Phenylpyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.43 4.1.1.43] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q5Q OCA].  
2Q5Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Azospirillum_brasilense Azospirillum brasilense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q5Q OCA].  


==Reference==
==Reference==
Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase., Versees W, Spaepen S, Wood MD, Leeper FJ, Vanderleyden J, Steyaert J, J Biol Chem. 2007 Nov 30;282(48):35269-78. Epub 2007 Sep 28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17905741 17905741]
Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase., Versees W, Spaepen S, Wood MD, Leeper FJ, Vanderleyden J, Steyaert J, J Biol Chem. 2007 Nov 30;282(48):35269-78. Epub 2007 Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17905741 17905741]
[[Category: Azospirillum brasilense]]
[[Category: Azospirillum brasilense]]
[[Category: Phenylpyruvate decarboxylase]]
[[Category: Phenylpyruvate decarboxylase]]
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[[Category: TLA]]
[[Category: TLA]]
[[Category: TPW]]
[[Category: TPW]]
[[Category: closed active site loops]]
[[Category: closed active site loop]]
[[Category: lyase]]
[[Category: lyase]]
[[Category: substrate complex]]
[[Category: substrate complex]]
[[Category: symmetrical dimer of dimers]]
[[Category: symmetrical dimer of dimer]]
[[Category: thiamine diphosphate]]
[[Category: thiamine diphosphate]]


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Retrieved from "https://proteopedia.org/2q5q"