2q8c: Difference between revisions

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[[Image:2q8c.jpg|left|200px]]<br /><applet load="2q8c" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q8c.jpg|left|200px]]
caption="2q8c, resolution 2.047&Aring;" />
 
'''Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate'''<br />
{{Structure
|PDB= 2q8c |SIZE=350|CAPTION= <scene name='initialview01'>2q8c</scene>, resolution 2.047&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=AKG:2-OXYGLUTARIC ACID'>AKG</scene>
|ACTIVITY=
|GENE= JMJD2A, JHDM3A, JMJD2, KIAA0677 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q8C is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NI:'>NI</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=AKG:'>AKG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8C OCA].  
2Q8C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8C OCA].  


==Reference==
==Reference==
Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase., Couture JF, Collazo E, Ortiz-Tello PA, Brunzelle JS, Trievel RC, Nat Struct Mol Biol. 2007 Aug;14(8):689-95. Epub 2007 Jun 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17589523 17589523]
Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase., Couture JF, Collazo E, Ortiz-Tello PA, Brunzelle JS, Trievel RC, Nat Struct Mol Biol. 2007 Aug;14(8):689-95. Epub 2007 Jun 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17589523 17589523]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: jumonji]]
[[Category: jumonji]]


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