2q8f: Difference between revisions

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[[Image:2q8f.gif|left|200px]]<br /><applet load="2q8f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q8f.gif|left|200px]]
caption="2q8f, resolution 2.03&Aring;" />
 
'''Structure of pyruvate dehydrogenase kinase isoform 1'''<br />
{{Structure
|PDB= 2q8f |SIZE=350|CAPTION= <scene name='initialview01'>2q8f</scene>, resolution 2.03&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=K:POTASSIUM ION'>K</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/[Pyruvate_dehydrogenase_(acetyl-transferring)]_kinase [Pyruvate dehydrogenase (acetyl-transferring)] kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.2 2.7.11.2]
|GENE= PDK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of pyruvate dehydrogenase kinase isoform 1'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q8F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=K:'>K</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/[Pyruvate_dehydrogenase_(acetyl-transferring)]_kinase [Pyruvate dehydrogenase (acetyl-transferring)] kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.2 2.7.11.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8F OCA].  
2Q8F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8F OCA].  


==Reference==
==Reference==
Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol., Kato M, Li J, Chuang JL, Chuang DT, Structure. 2007 Aug;15(8):992-1004. Epub 2007 Aug 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17683942 17683942]
Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol., Kato M, Li J, Chuang JL, Chuang DT, Structure. 2007 Aug;15(8):992-1004. Epub 2007 Aug 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17683942 17683942]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pyruvate dehydrogenase complex]]
[[Category: pyruvate dehydrogenase complex]]


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