2q8m: Difference between revisions

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[[Image:2q8m.jpg|left|200px]]<br /><applet load="2q8m" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q8m.jpg|left|200px]]
caption="2q8m, resolution 2.050&Aring;" />
 
'''T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound'''<br />
{{Structure
|PDB= 2q8m |SIZE=350|CAPTION= <scene name='initialview01'>2q8m</scene>, resolution 2.050&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BG6:BETA-D-GLUCOSE-6-PHOSPHATE'>BG6</scene>, <scene name='pdbligand=FBP:FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=AMP:ADENOSINE MONOPHOSPHATE'>AMP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11]
|GENE= fbp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=621 Shigella boydii])
}}
 
'''T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q8M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_boydii Shigella boydii] with <scene name='pdbligand=BG6:'>BG6</scene>, <scene name='pdbligand=FBP:'>FBP</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=AMP:'>AMP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8M OCA].  
2Q8M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_boydii Shigella boydii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8M OCA].  


==Reference==
==Reference==
Structure of inhibited fructose-1,6-bisphosphatase from Escherichia coli: distinct allosteric inhibition sites for AMP and glucose 6-phosphate and the characterization of a gluconeogenic switch., Hines JK, Kruesel CE, Fromm HJ, Honzatko RB, J Biol Chem. 2007 Aug 24;282(34):24697-706. Epub 2007 Jun 13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17567577 17567577]
Structure of inhibited fructose-1,6-bisphosphatase from Escherichia coli: distinct allosteric inhibition sites for AMP and glucose 6-phosphate and the characterization of a gluconeogenic switch., Hines JK, Kruesel CE, Fromm HJ, Honzatko RB, J Biol Chem. 2007 Aug 24;282(34):24697-706. Epub 2007 Jun 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17567577 17567577]
[[Category: Fructose-bisphosphatase]]
[[Category: Fructose-bisphosphatase]]
[[Category: Shigella boydii]]
[[Category: Shigella boydii]]
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[[Category: heterotrophic]]
[[Category: heterotrophic]]
[[Category: protein crystallography]]
[[Category: protein crystallography]]
[[Category: protein-protein interactions]]
[[Category: protein-protein interaction]]
[[Category: proteobacteria]]
[[Category: proteobacteria]]
[[Category: x-ray diffraction]]
[[Category: x-ray diffraction]]


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