4xxv: Difference between revisions
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''' | ==Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD== | ||
<StructureSection load='4xxv' size='340' side='right' caption='[[4xxv]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4xxv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XXV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XXV FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iwh|4iwh]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xxv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xxv RCSB], [http://www.ebi.ac.uk/pdbsum/4xxv PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/LEU3_BURTA LEU3_BURTA]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: 3-isopropylmalate dehydrogenase]] | |||
[[Category: Structural genomic]] | |||
[[Category: Nad]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Ssgcid]] | |||
Revision as of 14:07, 25 February 2015
Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD
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