5aga: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
m Protected "5aga" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
'''Unreleased structure'''
==Crystal structure of the Helicase domain of human DNA polymerase theta in complex with AMPPNP==
 
<StructureSection load='5aga' size='340' side='right' caption='[[5aga]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
The entry 5aga is ON HOLD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5aga]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AGA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AGA FirstGlance]. <br>
Authors: Newman, J.A., Cooper, C.D.O., Aitkenhead, H., Pinkas, D.M., Kupinska, K., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
Description: Crystal structure of the Helicase domain of human DNA polymerase theta in complex with AMPPNP
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aga FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aga OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5aga RCSB], [http://www.ebi.ac.uk/pdbsum/5aga PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Burgess-Brown, N]]
== Function ==
[[http://www.uniprot.org/uniprot/DPOLQ_HUMAN DPOLQ_HUMAN]] Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links.<ref>PMID:14576298</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: Aitkenhead, H]]
[[Category: Aitkenhead, H]]
[[Category: Pinkas, D.M]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Cooper, C D.O]]
[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Gileadi, O]]
[[Category: Kupinska, K]]
[[Category: Kupinska, K]]
[[Category: Arrowsmith, C.H]]
[[Category: Newman, J A]]
[[Category: Von Delft, F]]
[[Category: Pinkas, D M]]
[[Category: Gileadi, O]]
[[Category: Dna repair]]
[[Category: Newman, J.A]]
[[Category: Polq]]
[[Category: Edwards, A]]
[[Category: Transferase]]
[[Category: Cooper, C.D.O]]
Retrieved from "https://proteopedia.org/5aga"