2qgc: Difference between revisions

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[[Image:2qgc.jpg|left|200px]]<br /><applet load="2qgc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qgc.jpg|left|200px]]
caption="2qgc, resolution 1.300&Aring;" />
 
'''Human transthyretin (TTR) complexed with 2-(3,5-Dimethyl-4-hydroxyphenyl)benzoxazole'''<br />
{{Structure
|PDB= 2qgc |SIZE=350|CAPTION= <scene name='initialview01'>2qgc</scene>, resolution 1.300&Aring;
|SITE= <scene name='pdbsite=AC1:Mr4+Binding+Site+For+Residue+A+128'>AC1</scene> and <scene name='pdbsite=AC2:Mr4+Binding+Site+For+Residue+B+128'>AC2</scene>
|LIGAND= <scene name='pdbligand=MR4:'>MR4</scene>
|ACTIVITY=
|GENE= TTR, PALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human transthyretin (TTR) complexed with 2-(3,5-Dimethyl-4-hydroxyphenyl)benzoxazole'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QGC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MR4:'>MR4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Mr4+Binding+Site+For+Residue+A+128'>AC1</scene> and <scene name='pdbsite=AC2:Mr4+Binding+Site+For+Residue+B+128'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGC OCA].  
2QGC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGC OCA].  


==Reference==
==Reference==
Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors., Johnson SM, Connelly S, Wilson IA, Kelly JW, J Med Chem. 2008 Jan 24;51(2):260-70. Epub 2007 Dec 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18095641 18095641]
Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors., Johnson SM, Connelly S, Wilson IA, Kelly JW, J Med Chem. 2008 Jan 24;51(2):260-70. Epub 2007 Dec 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18095641 18095641]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Connelly, S.]]
[[Category: Connelly, S.]]
[[Category: MR4]]
[[Category: MR4]]
[[Category: amyloidogenesis inhibitors]]
[[Category: amyloidogenesis inhibitor]]
[[Category: hormone/growth factor complex]]
[[Category: hormone/growth factor complex]]
[[Category: tetramer]]
[[Category: tetramer]]
[[Category: transthyretin]]
[[Category: transthyretin]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:25:36 2008''
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