4mio: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei in complex with NAD(H) and myo-inositol==

~~The entry~~ 4mio is ~~ON HOLD until Mar 04 2016~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4mio]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MIO OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MIO FirstGlance].

~~Authors~~: ~~Bertwistle~~, D., ~~Sanders~~, D.A.R., ~~Palmer~~, D.R.J.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

~~Description~~: ~~Crystal Structure~~ of myo-inositol ~~dehydrogenase from Lactobacillus casei in complex with NAD~~(H) and myo-inositol

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Inositol_2-dehydrogenase Inositol 2-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.18 1.1.1.18] </td></tr>

[~~[Category~~: ~~Unreleased Structures]~~]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mio RCSB], [http://www.ebi.ac.uk/pdbsum/4mio PDBsum]</td></tr>

~~[[Category: Palmer, D.R.J]]~~

</table>

[[Category: ~~Sanders, D.A.R~~]]

== Function ==

[[http://www.uniprot.org/uniprot/B3W8L3_LACCB B3W8L3_LACCB]] Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.[HAMAP-Rule:MF_01671]

__TOC__

</StructureSection>

[[Category: Inositol 2-dehydrogenase]]

[[Category: Bertwistle, D]]

[[Category: Palmer, D R.J]]

[[Category: Sanders, D A.R]]

[[Category: Dehydrogenase]]

[[Category: Dehydrogenate]]

[[Category: Myo-inositol binding]]

[[Category: Nad]]

[[Category: Nad binding]]

[[Category: Oxidoreductase]]

[[Category: Rossmann fold]]

[[Category: Sugar alcohol dehydrogenase]]

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-'''Unreleased structure'''
+==Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei in complex with NAD(H) and myo-inositol==
+<StructureSection load='4mio' size='340' side='right' caption='[[4mio]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-The entry 4mio is ON HOLD  until Mar 04 2016
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4mio]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MIO FirstGlance]. <br>
-Authors: Bertwistle, D., Sanders, D.A.R., Palmer, D.R.J.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cea|3cea]], [[3mz0|3mz0]], [[3nt4|3nt4]], [[3ntq|3ntq]], [[4mie|4mie]], [[4min|4min]], [[4miy|4miy]], [[4mjl|4mjl]], [[4mkx|4mkx]], [[4mkz|4mkz]]</td></tr>
-Description: Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei in complex with NAD(H) and myo-inositol
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inositol_2-dehydrogenase Inositol 2-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.18 1.1.1.18] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mio RCSB], [http://www.ebi.ac.uk/pdbsum/4mio PDBsum]</span></td></tr>
-[[Category: Palmer, D.R.J]]
+</table>
-[[Category: Sanders, D.A.R]]
+== Function ==
+[[http://www.uniprot.org/uniprot/B3W8L3_LACCB B3W8L3_LACCB]] Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.[HAMAP-Rule:MF_01671]
+__TOC__
+</StructureSection>
+[[Category: Inositol 2-dehydrogenase]]
 [[Category: Bertwistle, D]]
+[[Category: Palmer, D R.J]]
+[[Category: Sanders, D A.R]]
+[[Category: Dehydrogenase]]
+[[Category: Dehydrogenate]]
+[[Category: Myo-inositol binding]]
+[[Category: Nad]]
+[[Category: Nad binding]]
+[[Category: Oxidoreductase]]
+[[Category: Rossmann fold]]
+[[Category: Sugar alcohol dehydrogenase]]