4owz: Difference between revisions
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''' | ==Structure of ECP/H15A mutant.== | ||
<StructureSection load='4owz' size='340' side='right' caption='[[4owz]], [[Resolution|resolution]] 1.47Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4owz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OWZ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a2y|4a2y]], [[4oxb|4oxb]], [[4oxf|4oxf]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4owz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4owz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4owz RCSB], [http://www.ebi.ac.uk/pdbsum/4owz PDBsum]</span></td></tr> | |||
[[ | </table> | ||
[[Category: Blanco, J | == Function == | ||
[[http://www.uniprot.org/uniprot/ECP_HUMAN ECP_HUMAN]] Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.<ref>PMID:2501794</ref> <ref>PMID:19450231</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Blanco, J A]] | |||
[[Category: Boix, E]] | [[Category: Boix, E]] | ||
[[Category: Moussaoui, M]] | [[Category: Moussaoui, M]] | ||
[[Category: Salazar, V A]] | |||
[[Category: Eosinophil cationic protein]] | |||
[[Category: Rnase 3]] | |||
