2qkb: Difference between revisions

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[[Image:2qkb.gif|left|200px]]<br /><applet load="2qkb" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qkb.gif|left|200px]]
caption="2qkb, resolution 2.40&Aring;" />
 
'''Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid'''<br />
{{Structure
|PDB= 2qkb |SIZE=350|CAPTION= <scene name='initialview01'>2qkb</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4]
|GENE= RNASEH1, RNH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QKB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKB OCA].  
2QKB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKB OCA].  


==Reference==
==Reference==
Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription., Nowotny M, Gaidamakov SA, Ghirlando R, Cerritelli SM, Crouch RJ, Yang W, Mol Cell. 2007 Oct 26;28(2):264-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17964265 17964265]
Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription., Nowotny M, Gaidamakov SA, Ghirlando R, Cerritelli SM, Crouch RJ, Yang W, Mol Cell. 2007 Oct 26;28(2):264-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17964265 17964265]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ribonuclease H]]
[[Category: Ribonuclease H]]
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[[Category: rnase h; rna/dna hybrid]]
[[Category: rnase h; rna/dna hybrid]]


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