2qrv: Difference between revisions

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[[Image:2qrv.jpg|left|200px]]<br /><applet load="2qrv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qrv.jpg|left|200px]]
caption="2qrv, resolution 2.89&Aring;" />
 
'''Structure of Dnmt3a-Dnmt3L C-terminal domain complex'''<br />
{{Structure
|PDB= 2qrv |SIZE=350|CAPTION= <scene name='initialview01'>2qrv</scene>, resolution 2.89&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37]
|GENE= DNMT3A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), DNMT3L ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of Dnmt3a-Dnmt3L C-terminal domain complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QRV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QRV OCA].  
2QRV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QRV OCA].  


==Reference==
==Reference==
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation., Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X, Nature. 2007 Sep 13;449(7159):248-51. Epub 2007 Aug 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17713477 17713477]
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation., Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X, Nature. 2007 Sep 13;449(7159):248-51. Epub 2007 Aug 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17713477 17713477]
[[Category: DNA (cytosine-5-)-methyltransferase]]
[[Category: DNA (cytosine-5-)-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: transferase/transferase regulator complex]]
[[Category: transferase/transferase regulator complex]]


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