2qxj: Difference between revisions

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[[Image:2qxj.jpg|left|200px]]<br /><applet load="2qxj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qxj.jpg|left|200px]]
caption="2qxj, resolution 2.10&Aring;" />
 
'''Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone and Copper'''<br />
{{Structure
|PDB= 2qxj |SIZE=350|CAPTION= <scene name='initialview01'>2qxj</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene> and <scene name='pdbligand=K7J:'>K7J</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Stratum_corneum_chymotryptic_enzyme Stratum corneum chymotryptic enzyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.117 3.4.21.117]
|GENE= KLK7, PRSS6, SCCE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone and Copper'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QXJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CU:'>CU</scene> and <scene name='pdbligand=K7J:'>K7J</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Stratum_corneum_chymotryptic_enzyme Stratum corneum chymotryptic enzyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.117 3.4.21.117] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QXJ OCA].  
2QXJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QXJ OCA].  


==Reference==
==Reference==
Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7., Debela M, Hess P, Magdolen V, Schechter NM, Steiner T, Huber R, Bode W, Goettig P, Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16086-91. Epub 2007 Oct 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17909180 17909180]
Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7., Debela M, Hess P, Magdolen V, Schechter NM, Steiner T, Huber R, Bode W, Goettig P, Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16086-91. Epub 2007 Oct 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17909180 17909180]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: K7J]]
[[Category: K7J]]
[[Category: alternative splicing]]
[[Category: alternative splicing]]
[[Category: catalytic triad his]]
[[Category: catalytic triad their]]
[[Category: copper]]
[[Category: copper]]
[[Category: glycoprotein]]
[[Category: glycoprotein]]
[[Category: histidine ligands]]
[[Category: histidine ligand]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: protease]]
[[Category: protease]]
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[[Category: zymogen]]
[[Category: zymogen]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:43:08 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:30:39 2008''