4cl0: Difference between revisions

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'''Unreleased structure'''
==Structure of the Mycobacterium tuberculosis Type II Dehydroquinase inhibited by a 3-dehydroquinic acid derivative==
 
<StructureSection load='4cl0' size='340' side='right' caption='[[4cl0]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
The entry 4cl0 is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4cl0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CL0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CL0 FirstGlance]. <br>
Authors: Otero, J.M., Llamas-Saiz, A.L., Maneiro, M., Peon, A., Sedes, A., Lamb, H., Hawkins, A.R., Gonzalez-Bello, C., van Raaij, M.J.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9PY:(2R)-2-METHYL-3-DEHYDROQUINIC+ACID'>9PY</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ckw|4ckw]], [[4ckx|4ckx]], [[4cky|4cky]], [[4ckz|4ckz]]</td></tr>
Description: Structure of the Mycobacterium tuberculosis Type II Dehydroquinase inhibited by a 3-dehydroquinic acid derivative
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cl0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cl0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cl0 RCSB], [http://www.ebi.ac.uk/pdbsum/4cl0 PDBsum]</span></td></tr>
[[Category: Otero, J.M]]
</table>
[[Category: Sedes, A]]
== Function ==
[[Category: Hawkins, A.R]]
[[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]  
__TOC__
</StructureSection>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Gonzalez-Bello, C]]
[[Category: Hawkins, A R]]
[[Category: Lamb, H]]
[[Category: Lamb, H]]
[[Category: Gonzalez-Bello, C]]
[[Category: Llamas-Saiz, A L]]
[[Category: Maneiro, M]]
[[Category: Maneiro, M]]
[[Category: Otero, J M]]
[[Category: Peon, A]]
[[Category: Peon, A]]
[[Category: Van Raaij, M.J]]
[[Category: Raaij, M J.van]]
[[Category: Llamas-Saiz, A.L]]
[[Category: Sedes, A]]
[[Category: Bacterial protein]]
[[Category: Inhibitor]]
[[Category: Lyase]]
[[Category: Protein binding]]
[[Category: Shikimis acid pathway]]
[[Category: Substrate specificity]]
[[Category: Type 2 dehydroquinase]]

Revision as of 14:08, 26 March 2015

Structure of the Mycobacterium tuberculosis Type II Dehydroquinase inhibited by a 3-dehydroquinic acid derivative

4cl0, resolution 3.10Å

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