2rfs: Difference between revisions
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[[Image:2rfs.jpg|left|200px]] | [[Image:2rfs.jpg|left|200px]] | ||
'''X-ray structure of SU11274 bound to c-Met''' | {{Structure | ||
|PDB= 2rfs |SIZE=350|CAPTION= <scene name='initialview01'>2rfs</scene>, resolution 2.20Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=AM8:N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide'>AM8</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] | |||
|GENE= MET ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''X-ray structure of SU11274 bound to c-Met''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2RFS is a [ | 2RFS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFS OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: tyrosine-protein kinase]] | [[Category: tyrosine-protein kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:42 2008'' | ||
Revision as of 16:35, 20 March 2008
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| 2rfs, resolution 2.20Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | AM8 | ||||||||||||
| Gene: | MET (Homo sapiens) | ||||||||||||
| Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
X-ray structure of SU11274 bound to c-Met
Disease
Known diseases associated with this structure: Autism, suseptibility to, 9 OMIM:[164860], Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860]
About this Structure
2RFS is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:35:42 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Single protein
- Bellon, S F.
- Dussault, I.
- Kaplan-Lefko, P.
- Moriguchi, J.
- Yang, Y.
- Zhang, Y.
- AM8
- Atp-binding
- C-met
- Glycoprotein
- Membrane
- Nucleotide-binding
- Phosphorylation
- Proto-oncogene
- Receptor tyrosine kinase
- Su11274
- Transferase
- Transmembrane
- Tyrosine-protein kinase
