2rgf: Difference between revisions
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[[Image:2rgf.jpg|left|200px]] | [[Image:2rgf.jpg|left|200px]] | ||
'''RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES''' | {{Structure | ||
|PDB= 2rgf |SIZE=350|CAPTION= <scene name='initialview01'>2rgf</scene> | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= | |||
|GENE= HUMAN RALGEF GENE (RALGDS) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2RGF is a [ | 2RGF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGF OCA]. | ||
==Reference== | ==Reference== | ||
Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling., Geyer M, Herrmann C, Wohlgemuth S, Wittinghofer A, Kalbitzer HR, Nat Struct Biol. 1997 Sep;4(9):694-9. PMID:[http:// | Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling., Geyer M, Herrmann C, Wohlgemuth S, Wittinghofer A, Kalbitzer HR, Nat Struct Biol. 1997 Sep;4(9):694-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9302994 9302994] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Kalbitzer, H R.]] | [[Category: Kalbitzer, H R.]] | ||
[[Category: Wittinghofer, A.]] | [[Category: Wittinghofer, A.]] | ||
[[Category: | [[Category: ralgd]] | ||
[[Category: ralgef]] | [[Category: ralgef]] | ||
[[Category: | [[Category: ra]] | ||
[[Category: ras-binding domain]] | [[Category: ras-binding domain]] | ||
[[Category: rbd]] | [[Category: rbd]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:54 2008'' | ||
Revision as of 16:35, 20 March 2008
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| 2rgf | |||||||||||||
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| Gene: | HUMAN RALGEF GENE (RALGDS) (Homo sapiens) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES
Overview
The solution structure of the Ras-binding domain (RBD) of Ral guanine-nucleotide exchange factor RalGEF was solved by NMR spectroscopy. The overall structure is similar to that of Raf-RBD, another effector of Ras, although the sequence identity is only 13%. 15N chemical shifts changes in the complex of RalGEF-RBD with Ras indicate an interaction similar to the intermolecular beta-sheet observed for the complex between Ras and Raf-RBD.
About this Structure
2RGF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling., Geyer M, Herrmann C, Wohlgemuth S, Wittinghofer A, Kalbitzer HR, Nat Struct Biol. 1997 Sep;4(9):694-9. PMID:9302994
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