2rgn: Difference between revisions

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[[Image:2rgn.jpg|left|200px]]<br /><applet load="2rgn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2rgn.jpg|left|200px]]
caption="2rgn, resolution 3.500&Aring;" />
 
'''Crystal Structure of p63RhoGEF complex with Galpha-q and RhoA'''<br />
{{Structure
|PDB= 2rgn |SIZE=350|CAPTION= <scene name='initialview01'>2rgn</scene>, resolution 3.500&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene>
|ACTIVITY=
|GENE= Gnaq ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), GEFT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), RHOA, ARH12, ARHA, RHO12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of p63RhoGEF complex with Galpha-q and RhoA'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2RGN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ALF:'>ALF</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GDP:'>GDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGN OCA].  
2RGN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGN OCA].  


==Reference==
==Reference==
Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs., Lutz S, Shankaranarayanan A, Coco C, Ridilla M, Nance MR, Vettel C, Baltus D, Evelyn CR, Neubig RR, Wieland T, Tesmer JJ, Science. 2007 Dec 21;318(5858):1923-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18096806 18096806]
Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs., Lutz S, Shankaranarayanan A, Coco C, Ridilla M, Nance MR, Vettel C, Baltus D, Evelyn CR, Neubig RR, Wieland T, Tesmer JJ, Science. 2007 Dec 21;318(5858):1923-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18096806 18096806]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: transducer]]
[[Category: transducer]]


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