2rgr: Difference between revisions

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[[Image:2rgr.jpg|left|200px]]<br /><applet load="2rgr" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2rgr.jpg|left|200px]]
caption="2rgr, resolution 3.0&Aring;" />
 
'''Topoisomerase IIA bound to G-segment DNA'''<br />
{{Structure
|PDB= 2rgr |SIZE=350|CAPTION= <scene name='initialview01'>2rgr</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3]
|GENE= TOP2, TOR3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''Topoisomerase IIA bound to G-segment DNA'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2RGR is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGR OCA].  
2RGR is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGR OCA].  


==Reference==
==Reference==
Structural basis for gate-DNA recognition and bending by type IIA topoisomerases., Dong KC, Berger JM, Nature. 2007 Dec 20;450(7173):1201-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18097402 18097402]
Structural basis for gate-DNA recognition and bending by type IIA topoisomerases., Dong KC, Berger JM, Nature. 2007 Dec 20;450(7173):1201-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18097402 18097402]
[[Category: DNA topoisomerase (ATP-hydrolyzing)]]
[[Category: DNA topoisomerase (ATP-hydrolyzing)]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: topoisomerase]]
[[Category: topoisomerase]]


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