Sandbox Reserved 1066: Difference between revisions
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This is the <scene name='69/698726/Overall_structure_cartoon/1'>overall structure of FadD13</scene> | This is the <scene name='69/698726/Overall_structure_cartoon/1'>overall structure of FadD13</scene> | ||
FadD13 is composed of 503 amino acid residues divided into three main regions: The <scene name='69/694233/Domains/1'>N-terminal domain</scene> (residues 1-395) and <scene name='69/694233/C-terminal_domain/1'>C-terminal domain</scene> (residues 402-503) which are connected via a flexible linker (residues 396-401).<ref name="Our Paper"/> | FadD13 is composed of 503 amino acid residues divided into three main regions: The <scene name='69/694233/Domains/1'>N-terminal domain</scene> (residues 1-395) and <scene name='69/694233/C-terminal_domain/1'>C-terminal domain</scene> (residues 402-503) which are connected via a flexible <scene name='69/694232/Linker_section/2'>linker</scene> (residues 396-401).<ref name="Our Paper"/> | ||
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== Active Site == | == Active Site == | ||
The active site on FadD13 is composed of two conserved regions, one of which serves as the binding site for ATP and the other for CoA. The | The active site on FadD13 is composed of two conserved regions, one of which serves as the binding site for ATP and the other for CoA. The adenine of ATP is bound to a group of <scene name='69/694232/Adenine_binding_group/2'>six amino acids (300-305)</scene> that is structurally identically to other acyl-CoA synthetases (Citation for original paper). | ||
= Disease = | = Disease = | ||
''Mycobacterium tuberculosis'' is the causative agent involved in the disease '''tuberculosis'''. | ''Mycobacterium tuberculosis'' is the causative agent involved in the disease '''tuberculosis'''. | ||
