Sandbox Reserved 433: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 66: | Line 66: | ||
It is observed that there are direct H-bonds, water-mediated polar interactions and hydrophobic interactions in the GSK-3β and staurosporine complex. | It is observed that there are direct H-bonds, water-mediated polar interactions and hydrophobic interactions in the GSK-3β and staurosporine complex. | ||
There are only two direct H-bonds, and they are observed between | There are only two direct H-bonds, and they are observed between | ||
1) the <span style="color:red">'''carbonyl oxygen'''</span> of Asp 133 and <span style="color:blue">'''N<sup>1</sup> (nitrogen)'''</span> of staurosporine. The length of this hydrogen bond is 2.93 Å, | 1) the <span style="color:red">'''carbonyl oxygen'''</span> of Asp 133 and <span style="color:blue">'''N<sup>1</sup> (nitrogen)'''</span> of staurosporine. The length of this hydrogen bond is 2.93 Å, | ||
2) the backbone <span style="color:blue">'''nitrogen'''</span> of Val 135 and <span style="color:red">'''O<sup>5</sup> (oxygen)'''</span> of staurosporine. The length of this hydrogen bond is 2.76 Å. | 2) the backbone <span style="color:blue">'''nitrogen'''</span> of Val 135 and <span style="color:red">'''O<sup>5</sup> (oxygen)'''</span> of staurosporine. The length of this hydrogen bond is 2.76 Å. | ||
