2tpt: Difference between revisions

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[[Image:2tpt.gif|left|200px]]~~<br /><applet load~~="2tpt~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2tpt.gif|left|200px]]

~~caption="~~2tpt, resolution 2.6Å" />

'''STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE'''~~<br />~~

{{Structure

|PDB= 2tpt |SIZE=350|CAPTION= <scene name='initialview01'>2tpt</scene>, resolution 2.6Å

|SITE= <scene name='pdbsite=SO4:Sulfate+Bound+In+The+Phosphate+Binding+Site'>SO4</scene> and <scene name='pdbsite=THY:T+Binding+Site'>THY</scene>

|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4]

|GENE=

}}

'''STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE'''

==Overview==

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==About this Structure==

2TPT is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Sites: <scene name='pdbsite=SO4:Sulfate+Bound+In+The+Phosphate+Binding+Site'>SO4</scene> and <scene name='pdbsite=THY:T+Binding+Site'>THY</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TPT OCA].

2TPT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TPT OCA].

==Reference==

Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase., Pugmire MJ, Cook WJ, Jasanoff A, Walter MR, Ealick SE, J Mol Biol. 1998 Aug 14;281(2):285-99. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~9698549 9698549]

Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase., Pugmire MJ, Cook WJ, Jasanoff A, Walter MR, Ealick SE, J Mol Biol. 1998 Aug 14;281(2):285-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9698549 9698549]

[[Category: Escherichia coli]]

[[Category: Single protein]]

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[[Category: transferase]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:39:19 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2tpt.gif|left|200px]]<br /><applet load="2tpt" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2tpt.gif|left|200px]]
-caption="2tpt, resolution 2.6&Aring;" />
-'''STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE'''<br />
+ {{Structure
+|PDB= 2tpt |SIZE=350|CAPTION= <scene name='initialview01'>2tpt</scene>, resolution 2.6&Aring;
+|SITE= <scene name='pdbsite=SO4:Sulfate+Bound+In+The+Phosphate+Binding+Site'>SO4</scene> and <scene name='pdbsite=THY:T+Binding+Site'>THY</scene>
+|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4]
+|GENE=
+}}
+'''STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-TPT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Sites: <scene name='pdbsite=SO4:Sulfate+Bound+In+The+Phosphate+Binding+Site'>SO4</scene> and <scene name='pdbsite=THY:T+Binding+Site'>THY</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TPT OCA].
+TPT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TPT OCA].
 ==Reference==
-Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase., Pugmire MJ, Cook WJ, Jasanoff A, Walter MR, Ealick SE, J Mol Biol. 1998 Aug 14;281(2):285-99. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9698549 9698549]
+Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase., Pugmire MJ, Cook WJ, Jasanoff A, Walter MR, Ealick SE, J Mol Biol. 1998 Aug 14;281(2):285-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9698549 9698549]
 [[Category: Escherichia coli]]
 [[Category: Single protein]]
@@ Line 24: / Line 33: @@
 [[Category: transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:50:03 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:39:19 2008''