2uue: Difference between revisions

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[[Image:2uue.gif|left|200px]]<br /><applet load="2uue" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2uue.gif|left|200px]]
caption="2uue, resolution 2.06&Aring;" />
 
'''REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS'''<br />
{{Structure
|PDB= 2uue |SIZE=350|CAPTION= <scene name='initialview01'>2uue</scene>, resolution 2.06&Aring;
|SITE= <scene name='pdbsite=AC1:Nh2+Binding+Site+For+Chain+F'>AC1</scene>
|LIGAND= <scene name='pdbligand=MTZ:4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE'>MTZ</scene> and <scene name='pdbligand=GVC:1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID'>GVC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS'''
 


==About this Structure==
==About this Structure==
2UUE is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MTZ:'>MTZ</scene> and <scene name='pdbligand=GVC:'>GVC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2C5T. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Known structural/functional Site: <scene name='pdbsite=AC1:Nh2+Binding+Site+For+Chain+F'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUE OCA].  
2UUE is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2C5T. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUE OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: transferase]]
[[Category: transferase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:39:48 2008''
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