4ymd: Difference between revisions
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''' | ==CL-K1 trimer bound to man(alpha1-2)man== | ||
<StructureSection load='4ymd' size='340' side='right' caption='[[4ymd]], [[Resolution|resolution]] 2.87Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ymd]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YMD FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ymd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ymd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ymd RCSB], [http://www.ebi.ac.uk/pdbsum/4ymd PDBsum]</span></td></tr> | |||
</table> | |||
[[Category: | == Disease == | ||
[[Category: | [[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Craniofacial-ulnar-renal syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
[[Category: Marshall, J | == Function == | ||
[[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity). | |||
[[Category: Moody, P | __TOC__ | ||
</StructureSection> | |||
[[Category: Gingras, A R]] | |||
[[Category: Girija, U Venkatraman]] | |||
[[Category: Marshall, J E]] | |||
[[Category: Moody, P C.E]] | |||
[[Category: Wallis, R]] | [[Category: Wallis, R]] | ||
[[Category: C-type carbohydrate-recognition domain]] | |||
[[Category: C-type lectin]] | |||
[[Category: Collectin]] | |||
[[Category: Sugar binding protein]] | |||
Revision as of 11:19, 8 April 2015
CL-K1 trimer bound to man(alpha1-2)man
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