2uwl: Difference between revisions
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[[Image:2uwl.gif|left|200px]] | [[Image:2uwl.gif|left|200px]] | ||
'''SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA''' | {{Structure | ||
|PDB= 2uwl |SIZE=350|CAPTION= <scene name='initialview01'>2uwl</scene>, resolution 1.90Å | |||
|SITE= <scene name='pdbsite=AC1:895+Binding+Site+For+Chain+A'>AC1</scene> | |||
|LIGAND= <scene name='pdbligand=895:2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDE'>895</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] | |||
|GENE= | |||
}} | |||
'''SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2UWL is a [ | 2UWL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWL OCA]. | ||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: blood coagulation]] | [[Category: blood coagulation]] | ||
[[Category: calcium]] | [[Category: calcium]] | ||
[[Category: cleavage on pair of basic | [[Category: cleavage on pair of basic residue]] | ||
[[Category: complex]] | [[Category: complex]] | ||
[[Category: egf-like domain]] | [[Category: egf-like domain]] | ||
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[[Category: zymogen]] | [[Category: zymogen]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:40:37 2008'' | ||
Revision as of 16:40, 20 March 2008
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| 2uwl, resolution 1.90Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sites: | AC1 | ||||||||||||
| Ligands: | 895 | ||||||||||||
| Activity: | Coagulation factor Xa, with EC number 3.4.21.6 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA
Disease
Known disease associated with this structure: Factor X deficiency OMIM:[227600]
About this Structure
2UWL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:40:37 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Single protein
- Brown, D.
- Burns-Kurtis, C L.
- Chan, C.
- Convery, M A.
- Hubbard, J A.
- Kelly, H A.
- Pateman, A J.
- Patikis, A.
- Senger, S.
- Shah, G P.
- Toomey, J R.
- Watson, N S.
- Young, R J.
- Zhou, P.
- 895
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Complex
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Polymorphism
- Protease
- Serine protease
- Target hopping
- Zymogen
