2v2e: Difference between revisions

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[[Image:2v2e.jpg|left|200px]]<br /><applet load="2v2e" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2v2e.jpg|left|200px]]
caption="2v2e, resolution 1.68&Aring;" />
 
'''STRUCTURE OF ISONIAZID (INH) BOUND TO CYTOCHROME C PEROXIDASE MUTANT N184R Y36A'''<br />
{{Structure
|PDB= 2v2e |SIZE=350|CAPTION= <scene name='initialview01'>2v2e</scene>, resolution 1.68&Aring;
|SITE= <scene name='pdbsite=AC1:Hem+Binding+Site+For+Chain+A'>AC1</scene> and <scene name='pdbsite=AC2:Isz+Binding+Site+For+Chain+A'>AC2</scene>
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> and <scene name='pdbligand=ISZ:4-(DIAZENYLCARBONYL)PYRIDINE'>ISZ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5]
|GENE=
}}
 
'''STRUCTURE OF ISONIAZID (INH) BOUND TO CYTOCHROME C PEROXIDASE MUTANT N184R Y36A'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2V2E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=HEM:'>HEM</scene> and <scene name='pdbligand=ISZ:'>ISZ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] Known structural/functional Sites: <scene name='pdbsite=AC1:Hem+Binding+Site+For+Chain+A'>AC1</scene> and <scene name='pdbsite=AC2:Isz+Binding+Site+For+Chain+A'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2E OCA].  
2V2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2E OCA].  


==Reference==
==Reference==
The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases., Metcalfe C, Macdonald IK, Murphy EJ, Brown KA, Raven EL, Moody PC, J Biol Chem. 2008 Mar 7;283(10):6193-6200. Epub 2007 Dec 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18056997 18056997]
The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases., Metcalfe C, Macdonald IK, Murphy EJ, Brown KA, Raven EL, Moody PC, J Biol Chem. 2008 Mar 7;283(10):6193-6200. Epub 2007 Dec 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18056997 18056997]
[[Category: Cytochrome-c peroxidase]]
[[Category: Cytochrome-c peroxidase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: transit peptide]]
[[Category: transit peptide]]


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