Helicase: Difference between revisions

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Michal Harel (talk | contribs)
32,831 edits
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Line 146: Line 146:
**[[2kbf]] - yDBP5 C terminal – NMR<BR />
**[[2kbf]] - yDBP5 C terminal – NMR<BR />
**[[3gfp]] - yDBP5 C-terminal<BR />
**[[3gfp]] - yDBP5 C-terminal<BR />
**[[2i4i]] – hDDX3X<BR />
**[[2i4i]] – hDDX3X residues 167-581<BR />
**[[2jgn]] – hDDX3X helicase domain<BR />
**[[4px9]] - hDDX3X residues 135-407<br />
**[[4pxa]] - hDDX3X residues 135-407 (mutant)<br />
**[[2jgn]] – hDDX3X helicase domain residues 408-579<BR />
**[[3ly5]] – hDDX18 dead domain<BR />
**[[3ly5]] – hDDX18 dead domain<BR />
**[[2rb4]] – hDDX25 helicase domain<BR />
**[[2rb4]] – hDDX25 helicase domain<BR />
Line 170: Line 172:
**[[3pew]], [[3pey]] - yDBP5 residues 91-482 (mutant) + ADP + BeF3 + RNA<BR />
**[[3pew]], [[3pey]] - yDBP5 residues 91-482 (mutant) + ADP + BeF3 + RNA<BR />
**[[3peu]], [[3pev]] - yDBP5 C-terminal (mutant) + GLE1 + IP6<BR />
**[[3peu]], [[3pev]] - yDBP5 C-terminal (mutant) + GLE1 + IP6<BR />
**[[3i5x]], [[3i5y]] – yMSS116 + AMPPNP + RNA<BR />
**[[3sqw]], [[3sqx]] - yMSS116 + AMPPNP + RNA<BR />
**[[3i61]], [[4tyw]], [[4tyy]], [[4tz0]], [[4tz6]] - yMSS116 + nucleotide + BeF3 + RNA<BR />
**[[3i62]] - yMSS116 + ADP + AlF4 + RNA<BR />
**[[4tyn]] - yMSS116 + ADP + DNA<br />
**[[2xau]], [[3kx2]] – yPRP43 + ADP<BR />
**[[3jrv]] – DDX3X + protein K7 – Vaccinia virus<BR />
**[[3jrv]] – DDX3X + protein K7 – Vaccinia virus<BR />
**[[3fmo]], [[3fhc]] – hDBP5 + Nup214<BR />
**[[3fmo]], [[3fhc]] – hDBP5 + Nup214<BR />
Line 189: Line 197:
**[[2xzl]] – yNAM7 CH and helicase domains + RNA<BR />
**[[2xzl]] – yNAM7 CH and helicase domains + RNA<BR />
**[[2xgj]] – yDOB1 residues 81-1073 + RNA<BR />
**[[2xgj]] – yDOB1 residues 81-1073 + RNA<BR />
**[[4u4c]] - yDOB1 residues 81-1073 + poly(A) RNA polymerase protein 2<br />
**[[3l9o]] - yDOB1 residues 1-1073 + peptide<BR />
**[[3l9o]] - yDOB1 residues 1-1073 + peptide<BR />
**[[2xau]], [[3kx2]] – yPRP43 + ADP<BR />
**[[4qu4]] - yDOB1 <br />
**[[3i5x]], [[3i5y]] – yMSS116 residues 37-597 + AMPPNP + RNA<BR />
**[[3sqw]], [[3sqx]] - yMSS116 residues 88-664 + AMPPNP + RNA<br />
**[[3i61]] - yMSS116 residues 37-597 + ADP + BeF3 + RNA<BR />
**[[3i62]] - yMSS116 residues 37-597 + ADP + AlF4 + RNA<BR />
**[[2vso]], [[2vsx]] – yEIF4A + initiation factor 4F middle domain<BR />
**[[2vso]], [[2vsx]] – yEIF4A + initiation factor 4F middle domain<BR />
**[[2g9n]] - hEIF4A dead domain
**[[2g9n]] - hEIF4A dead domain
Line 200: Line 205:
*Viral ATP-dependent RNA helicase NS3
*Viral ATP-dependent RNA helicase NS3


**[[3o8b]], [[3o8d]], [[1cu1]], [[8ohm]], [[1hei]], [[4a92]] – HvHel NS3 – Hepatitis C virus<BR />
**[[3o8b]], [[3o8d]], [[1cu1]], [[8ohm]], [[1hei]], [[4a92]], [[3rvb]] – HvHel NS3 residues 1186-1658 – Hepatitis C virus<BR />
**[[1onb]], [[1jr6]] - HvHel NS3 arginine-rich domain – NMR<BR />
**[[1onb]], [[1jr6]] - HvHel NS3 arginine-rich domain residues 1353-1507 – NMR<BR />
**[[2jlq]], [[2bhr]], [[2bmf]], [[2whx]], [[2wzq]] – DvHel NS3 residues 1646-2092 – Dengue virus<BR />
**[[2jlq]], [[2bhr]], [[2bmf]], [[2whx]], [[2wzq]] – DvHel NS3 residues 1646-2092 – Dengue virus<BR />
**[[2z83]] – Hel NS3 residues 167-624 – Japanese encephalitis virus<BR />
**[[2z83]] – Hel NS3 residues 167-624 – Japanese encephalitis virus<BR />
Line 243: Line 248:


**[[1x2i]] – HEF DNA-binding domain – ''Pyrococcus furiosus''
**[[1x2i]] – HEF DNA-binding domain – ''Pyrococcus furiosus''
*ATP-dependent RNA helicase Srmb
**[[2yjt]] - EcSrmb residues 219-388 + RRAA<br />
*ATP-dependent RNA helicase Dhh1
**[[4bru]] – yDhh1 (mutant) + EDC3<br />
**[[4brw]] – yDhh1 (mutant) + PAT1<br />


*Werner syndrome ATP-dependent DNA helicase
*Werner syndrome ATP-dependent DNA helicase
Line 255: Line 269:


**[[2v1x]] - hQ1 residues 49-616<BR />
**[[2v1x]] - hQ1 residues 49-616<BR />
**[[2wwy]] – hQ1 residues 49-616 + DNA<br />
**[[2wwy]], [[4u7d]] – hQ1 residues 49-616 + DNA<br />
**[[2kmu]] – hQ4 N terminal - NMR
**[[2kmu]] – hQ4 N terminal - NMR


Line 262: Line 276:
**[[1gm5]] – TmRecG  + DNA <BR />
**[[1gm5]] – TmRecG  + DNA <BR />


*ATP-dependent DNA helicase RecQ
*ATP-dependent DNA helicase RecQ (Bloom Syndrome helicase)


**[[3iuo]] – RecQ residues 604-725 – ''Porphyromonas gingivalis''<BR />
**[[3iuo]] – RecQ residues 604-725 – ''Porphyromonas gingivalis''<BR />
Line 271: Line 285:
**[[1oyy]] - EcRecQ catalytic domain + ATP<BR />
**[[1oyy]] - EcRecQ catalytic domain + ATP<BR />
**[[1d8b]] - yRecQ HRDC domain - NMR<BR />
**[[1d8b]] - yRecQ HRDC domain - NMR<BR />
**[[4cgz]], [[4o3m]] - hRecQ catalytic domain + DNA<br />
**[[4cdg]] - hRecQ catalytic domain + nanobody<br />


*ATP-dependent DNA helicase RuvA, RuvB
*ATP-dependent DNA helicase RuvA, RuvB
Line 289: Line 305:
**[[2oca]], [[1rif]]- T4UVSW (mutant) – Enterobacteria phage T4<BR />
**[[2oca]], [[1rif]]- T4UVSW (mutant) – Enterobacteria phage T4<BR />
**[[2jpn]] - T4UVSW
**[[2jpn]] - T4UVSW
*ATP-dependent DNA helicase DDA
**[[3upu]] – T4DDA + DNA<br />


*ATP-dependent DNA helicase UVRD
*ATP-dependent DNA helicase UVRD
Line 347: Line 367:


**[[3crv]], [[3crw]] – XPD – ''Sulfolobus acidocaldarius''<br />
**[[3crv]], [[3crw]] – XPD – ''Sulfolobus acidocaldarius''<br />
**[[4a15]] - XPD + DNA – ''Thermoplasma acidophilum''<br />


*Pre-mRNA-splicing Helicase (Brr2)
*Pre-mRNA-splicing Helicase


**[[3hib]], [[3im1]], [[3im2]] – yBrr2 2nd SEC63 domain<br />
**[[3hib]], [[3im1]], [[3im2]] – yBrr2 2nd SEC63 domain<br />
**[[4bgd]] – yBrr2 + pre-mRNA-splicing factor 8<br />
**[[4bgd]] – yBrr2 + pre-mRNA-splicing factor 8<br />
**[[4w7s]] – yCa8<br />
*crispr-associated helicase Cas3
**[[4q2c]] – TteCas3 – ''Thermobaculum terrenum''<br />
**[[4q2d]] – TteCas3 + DTP<br />
**[[4qqw]], [[4qqx]] – TfCas3 – ''Thermobifida fusca''<br />
**[[4qqy]] – TfCas3 + ADP + HD nuclease<br />
**[[4qqz]] – TfCas3 + AMPPNP <br />
}}
}}
==References==
==References==
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