High mobility group protein: Difference between revisions

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New page: <StructureSection load='2gzk' size='340' side='right' caption='Rat HMG1 tandem boxes complexed with DNA (PDB code 2gzk).' scene=''> '''High mobility group protein (HMG)''' is a chroma...
 
Michal Harel (talk | contribs)
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<StructureSection load='2gzk' size='340' side='right' caption='Rat HMG1 tandem boxes complexed with DNA (PDB code [[2gzk]]).' scene=''>
<StructureSection load='2gzk' size='340' side='right' caption='Rat HMG1 tandem boxes complexed with DNA (PDB code [[2gzk]]).' scene=''>
'''High mobility group protein (HMG)''' is a chromatin protein which organizes the DNA and regulater transcription.  For details see [[HMGI(Y)]].
'''High mobility group protein (HMG)''' is a chromatin protein which organizes the DNA and regulater transcription.  HMG superfamilies differ by their DNA-binding domains.  '''HMGA'''s bind via an AT-hook domain.  '''HMGB'''s bind via box domain.  '''HMGN'''s bind via a nucleosome binding domain.  For details on HMGA see [[HMGI(Y)]].
== Function ==
== Function ==


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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*HMGA
**[[2ezd]], [[2eze]], [[2ezf]], [[2ezg]] – hHMG-1 + DNA - human<br />
*HMGB
**[[1hme]], [[1hmf]] – rHMG-1 B domain – rat - NMR <br />
**[[1aab]] – rHMG-1 A domain - NMR <br />
**[[1ckt]] – rHMG-1 A domain + DNA <br />
**[[2gzk]] – rHMG-1 tandem boxes + DNA <br />
**[[2yrq]] – hHMG-1 tandem boxes - human - NMR<br />
**[[2rtu]] – hHMG-1 box 1 - NMR<br />
**[[2ly4]] – hHMG-1 box domain + cellular tumor antigen p53 - NMR<br />
**[[2eqz]], [[2yqi]] – hHMG-3 box domain - NMR<br />
**[[1hsm]], [[1hsn]], [[1nhm]], [[1nhn]] – HMG-1 box domain – chinese hamster - NMR <br />
**[[1hma]] – DmHMG-D DNA-binding domain – ''Drosophila melanogaster'' - NMR<br />
**[[1qrv]] – DmHMG-D DNA-binding domain + DNA <br />
**[[3nm9]] – DmHMG-D DNA-binding domain (mutant) + DNA <br />
**[[1e7j]] – DmHMG-D DNA-binding domain + DNA - NMR<br />
**[[1j3d]] – pHMG-2 C terminal – pig - NMR<br />
**[[1j3c]] – pHMG-2 C terminal (mutant) - NMR<br />
**[[1j3x]] – pHMG-2 N terminal (mutant) - NMR<br />
*HMG


[[1hme]], [[1hmf]] – rHMG1 B domain – rat - NMR <br />
**[[2mrc]] – HMG residues 17-99 – ''Plasmodium falciparum'' - NMR <br />
[[1aab]] – rHMG1 A domain - NMR <br />
}}
[[1ckt]] – rHMG1 A domain + DNA <br />
[[2gzk]] – rHMG1 tandem boxes + DNA <br />
[[2yrq]] – hHMG1 tandem boxes - human - NMR<br />
[[2rtu]] – hHMG1 box 1 - NMR<br />
[[2ly4]] – hHMG1 box domain + cellular tumor antigen p53 - NMR<br />
[[1hsm]], [[1hsn]], [[1nhm]], [[1nhn]] – HMG1 box domain – chinese hamster - NMR <br />
== References ==
== References ==
<references/>
<references/>


[[Category:Topic Page]]
[[Category:Topic Page]]
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