2v76: Difference between revisions

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[[Image:2v76.jpg|left|200px]]<br /><applet load="2v76" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2v76.jpg|left|200px]]
caption="2v76, resolution 1.60&Aring;" />
 
'''CRYSTAL STRUCTURE OF THE HUMAN DOK1 PTB DOMAIN'''<br />
{{Structure
|PDB= 2v76 |SIZE=350|CAPTION= <scene name='initialview01'>2v76</scene>, resolution 1.60&Aring;
|SITE= <scene name='pdbsite=AC1:Pge+Binding+Site+For+Chain+B'>AC1</scene>, <scene name='pdbsite=AC2:Pge+Binding+Site+For+Chain+D'>AC2</scene>, <scene name='pdbsite=AC3:Pge+Binding+Site+For+Chain+B'>AC3</scene>, <scene name='pdbsite=AC4:Pge+Binding+Site+For+Chain+A'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Chain+D'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Chain+B'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Chain+A'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Chain+C'>AC8</scene>, <scene name='pdbsite=AC9:Gol+Binding+Site+For+Chain+C'>AC9</scene> and <scene name='pdbsite=BC1:Edo+Binding+Site+For+Chain+A'>BC1</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF THE HUMAN DOK1 PTB DOMAIN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2V76 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=PGE:'>PGE</scene>, <scene name='pdbligand=EDO:'>EDO</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Pge+Binding+Site+For+Chain+B'>AC1</scene>, <scene name='pdbsite=AC2:Pge+Binding+Site+For+Chain+D'>AC2</scene>, <scene name='pdbsite=AC3:Pge+Binding+Site+For+Chain+B'>AC3</scene>, <scene name='pdbsite=AC4:Pge+Binding+Site+For+Chain+A'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Chain+D'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Chain+B'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Chain+A'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Chain+C'>AC8</scene>, <scene name='pdbsite=AC9:Gol+Binding+Site+For+Chain+C'>AC9</scene> and <scene name='pdbsite=BC1:Edo+Binding+Site+For+Chain+A'>BC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V76 OCA].  
2V76 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V76 OCA].  


==Reference==
==Reference==
An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on DOK1 and talin binding., Oxley CL, Anthis NJ, Lowe ED, Vakonakis I, Campbell ID, Wegener KL, J Biol Chem. 2007 Dec 21;. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18156175 18156175]
An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on DOK1 and talin binding., Oxley CL, Anthis NJ, Lowe ED, Vakonakis I, Campbell ID, Wegener KL, J Biol Chem. 2007 Dec 21;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18156175 18156175]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ptb domain]]
[[Category: ptb domain]]


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