Sandbox Reserved 1084: Difference between revisions

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[[Image:D101.png|400px|left|thumb| '''Fig. 2''' Mutation of Asp 101 to Ala inhibits HDAC8 activity.]]
[[Image:D101.png|400px|left|thumb| '''Fig. 2''' Mutation of Asp 101 to Ala inhibits HDAC8 activity.]]


Based on the crystallographic studies, a '''mechanism''' of the HDAC8 catalyzed reaction has been proposed.
Based on the crystallographic studies, a mechanism of the HDAC8 catalyzed reaction has been proposed.
[[Image:HDAC8_mechanism.png|400px|left|thumb| '''Fig. 3''' Catalytic mechanism of HDAC8.]]
[[Image:HDAC8_mechanism.png|400px|left|thumb| '''Fig. 3''' Catalytic mechanism of HDAC8.]]