Sandbox Reserved 1053: Difference between revisions
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===Inhibitors=== | ===Inhibitors=== | ||
Additional thiol-modifying agents, p-chloromercuribenzoic acid and iodoacetamide, were crystalized with Ag85C. The structures show that each of these thiol-reactive inhibitors covalently bound to C209 and caused a relaxation of the α9 helix in a similar fashion to ebselen. | Additional thiol-modifying agents, [http://en.wikipedia.org/wiki/4-Chloromercuribenzoic_acid p-chloromercuribenzoic acid] and [http://en.wikipedia.org/wiki/Iodoacetamide iodoacetamide], were crystalized with Ag85C. The structures show that each of these thiol-reactive inhibitors covalently bound to C209 and caused a relaxation of the α9 helix in a similar fashion to ebselen. | ||
[[Image:Inhibitors_Ag85c.jpeg|400 px|center]] | [[Image:Inhibitors_Ag85c.jpeg|400 px|center]] | ||
