Sandbox Reserved 1059: Difference between revisions

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<StructureSection load='4K8M' size='350' side='right' caption='NrdH of ''Mycobacterium tuberculosis''' (PDB entry [[4K8M]])' scene=''>
<StructureSection load='4K8M' size='350' side='right' caption='NrdH of ''Mycobacterium tuberculosis''' (PDB entry [[4K8M]])' scene=''>
==Introduction==
==Introduction==
NrdH is a redox protein and is part of a family of redox proteins. The other proteins that maintain the redox balance of NrdH are three [http://en.wikipedia.org/wiki/Thioredoxin thioredoxin] and three [http://en.wikipedia.org/wiki/Glutaredoxin glutaredoxins]-like proteins. Prokaryotes typically maintain redox homeostasis through low-molecular weight thiols (glutathione) and through proteins involved in disulfide exchange (thioredoxins)<ref name="Phulera" />. NrdH is found in many types of bacteria, such as [http://www.nature.com/nature/journal/v393/n6685/full/393537a0.html ''Mycobacterium tuberculosis''].  This bacteria causes the disease [http://en.wikipedia.org/wiki/Tuberculosis tuberculosis] <ref name="Cole"> DOI: 10.1038/31159</ref>.  
[http://proteopedia.org/wiki/index.php/4k8m NrdH] is a redox protein and is part of a family of redox proteins. The other proteins that maintain the redox balance of NrdH are three [http://en.wikipedia.org/wiki/Thioredoxin thioredoxin] and three [http://en.wikipedia.org/wiki/Glutaredoxin glutaredoxins]-like proteins. Prokaryotes typically maintain redox homeostasis through low-molecular weight thiols (glutathione) and through proteins involved in disulfide exchange (thioredoxins)<ref name="Phulera" />. NrdH is found in many types of bacteria, such as [http://www.nature.com/nature/journal/v393/n6685/full/393537a0.html ''Mycobacterium tuberculosis''].  This bacteria causes the disease [http://en.wikipedia.org/wiki/Tuberculosis tuberculosis] <ref name="Cole"> DOI: 10.1038/31159</ref>.  


===Background===
===Background===