NAD synthase

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NAD+ synthase (NADS) catalyzes the conversion of ATP, deamino-NAD+ and NH3 to AMP, NAD+ and diphophate (PP). NADS is part of the NAD synthesis pathway.

3D Structures of NAD+ synthase

Updated on 06-May-2015

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• NAD synthase
  • 3p52 – NADS – Campylobacter jejuni
    
  • 3q4g – NADS (mutant) – Vibrio cholerae
    
  • 1wxf – EcNADS – Escherichia coli
    
  • 1xnh – HpNADS - Helicobacter pylori
    
  • 2pzb – BaNADS - Bacillus anthracis
    
  • 3dpi – NADS – Burkholderia pseudomallei
    
• NADS binary complex
  • 1ifx – BsNADS + deamino-NAD – Bacillus subtilis
    
  • 1wxh – EcNADS + NAD
    
  • 3hmq – BsNADS + NAD – Salmonella typhimurium
    
• NADS ternary complex
  • 1ih8 – BsNADS + Mg + ATP derivative
    
  • 1wxe – EcNADS + Mg + AMP
    
  • 1wxg – EcNADS + Mg + deamino-NAD
    
  • 2pz8 – BaNADS + Mg + ATP derivative
    
• NADS quaternary complex
  • 1ee1 – BsNADS + Mg + ATP + deamino-NAD
    
  • 1fyd – BsNADS + Mg + AMP + PP
    
  • 1kqp – BsNADS + Mg + PP + NAD derivative
    
  • 1wxi – EcNADS + Mg + AMP + PP
    
  • 1xng – HpNADS + Mg + ATP + deamino-NAD
    
  • 2pza – BaNADS + Mg + AMP + PP
    
• NADS quinary complex
  • 1nsy – BsNADS + Mg + ATP + ADP + PP
    
  • 2nsy – BsNADS + Mg + AMP + NAD + PP
    
• NADS glutamine-dependent
  • 3sdb – MtNADS (mutant) – Mycobacterium tuberculosis
    
  • 3seq, 3sez – MtNADS (mutant) + ATP derivative + pyridinium derivative
    
  • 3szg – MtNADS (mutant) + AMP + pyridinium derivative
    
  • 3syt – MtNADS + AMP + NAD + glutamate
    

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