NEDD8

NEDD8 is a ubiquitin-like protein in human. It facilitates ubiquitin conjugation. It participates in the recruitment of E2 to the ubiquitin ligase complex. NEDD8 modifies the cullin subunits (CUL) of SCF ubiquitin E3 ligase. In yeast the protein is called Rub1.

3D Structures of NEDD8

Updated on 06-May-2015

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• NEDD8
  • 1ndd - hNEDD8 - human
    
  • 2ko3 – hNEDD8 – NMR
    
• NEDD8+ubiquitin-activating enzyme E1
  • 3gzn – hNEDD8+hE1 regulatory and catalytic subunits
    
  • 3dbh, 3dbl, 3dbr - hNEDD8+hE1 regulatory and catalytic subunits (mutant)
    
  • 2nvu - hNEDD8+hE1 regulatory subunit+MBP/E1 catalytic subunit+UBC12
    
  • 1r4m - hNEDD8+hE1C+amyloid beta precursor protein
    
  • 1r4n - hNEDD8+hE1C+amyloid beta precursor protein+ATP
    
• NEDD8+other proteins
  • 3dqv – hNEDD8+CUL-5
    
  • 2bkr – hNEDD8+NEDP1
    
  • 1xt9 – hNEDD8+DEN1
    
  • 4f8c – hNEDD8 + cycle inhibiting factor
    
  • 4hcp – hNEDD8 + ATP/GTP binding protein
    
  • 4fbj – hNEDD8 + bacterial effector CIF
    
  • 4p5o – hNEDD8 + cullin-1 + E3 ubiquitin-protein ligase + DCN1-like protein + UBC12
    
• Rub1
  • 1bt0 – Rub1 – Arabidopsis thaliana
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky