User:Wayne Decatur/Gal 4: Difference between revisions
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The DNA binding domain <scene name='70/701975/1d66_firstglance_zn_binding/2'>uses six Cys residues to coordinate the binding of two ions of zinc (Zn(II))</scene>. (In the crystal structure [[1d66]], the zinc ions are actually represented by other members of the same group on the periodic table, the heavier cadmium ions.) The Zn-binding motif lets the structure accomplish more with fewer amino acids, the metals lending an "economy of structure", arranging two small helices to recognize a specific DNA site.<br> | The DNA binding domain <scene name='70/701975/1d66_firstglance_zn_binding/2'>uses six Cys residues to coordinate the binding of two ions of zinc (Zn(II))</scene>. (In the crystal structure [[1d66]], the zinc ions are actually represented by other members of the same group on the periodic table, the heavier cadmium ions.) The Zn-binding motif lets the structure accomplish more with fewer amino acids, the metals lending an "economy of structure", arranging two small helices to recognize a specific DNA site. <scene name='70/701975/1d66_base_conctacts/1'>Two lysines (17 and 18) make direct base contacts with the specified residues in the consensus 5′-CGG-N11-CCG-3′</scene>.<br> | ||
{{Button Toggle NucleicDrumsColorSchemeWcartoon}} {{ColorKey Bases DNA}} | {{Button Toggle NucleicDrumsColorSchemeWcartoon}} {{ColorKey Bases DNA}} | ||
