2z65: Difference between revisions

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[[Image:2z65.jpg|left|200px]]<br /><applet load="2z65" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2z65.jpg|left|200px]]
caption="2z65, resolution 2.70&Aring;" />
 
'''Crystal structure of the human TLR4 TV3 hybrid-MD-2-Eritoran complex'''<br />
{{Structure
|PDB= 2z65 |SIZE=350|CAPTION= <scene name='initialview01'>2z65</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene> and <scene name='pdbligand=E55:3-O-DECYL-2-DEOXY-6-O-{2-DEOXY-3-O-[(3R)-3-METHOXYDECYL]-6-O-METHYL-2-[(11Z)-OCTADEC-11-ENOYLAMINO]-4-O-PHOSPHONO-BETA-D-GLUCOPYRANOSYL}-2-[(3-OXOTETRADECANOYL)AMINO]-1-O-PHOSPHONO-ALPHA-D-GLUCOPYRANOSE'>E55</scene>
|ACTIVITY=
|GENE= TLR4, VLRB.61 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Homo sapiens, Eptatretus burgeri]), MD-2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the human TLR4 TV3 hybrid-MD-2-Eritoran complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Z65 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Homo_sapiens,_eptatretus_burgeri Homo sapiens, eptatretus burgeri] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=NDG:'>NDG</scene> and <scene name='pdbligand=E55:'>E55</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z65 OCA].  
2Z65 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Homo_sapiens,_eptatretus_burgeri Homo sapiens, eptatretus burgeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z65 OCA].  


==Reference==
==Reference==
Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran., Kim HM, Park BS, Kim JI, Kim SE, Lee J, Oh SC, Enkhbayar P, Matsushima N, Lee H, Yoo OJ, Lee JO, Cell. 2007 Sep 7;130(5):906-17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17803912 17803912]
Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran., Kim HM, Park BS, Kim JI, Kim SE, Lee J, Oh SC, Enkhbayar P, Matsushima N, Lee H, Yoo OJ, Lee JO, Cell. 2007 Sep 7;130(5):906-17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17803912 17803912]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens, eptatretus burgeri]]
[[Category: Homo sapiens, eptatretus burgeri]]
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[[Category: innate immunity]]
[[Category: innate immunity]]
[[Category: leucine-rich repeat]]
[[Category: leucine-rich repeat]]
[[Category: lps]]
[[Category: lp]]
[[Category: md-2]]
[[Category: md-2]]
[[Category: membrane]]
[[Category: membrane]]
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[[Category: transmembrane]]
[[Category: transmembrane]]


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