2z6q: Difference between revisions

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[[Image:2z6q.jpg|left|200px]]<br /><applet load="2z6q" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2z6q.jpg|left|200px]]
caption="2z6q, resolution 2.79&Aring;" />
 
'''Ternary structure of Arg165Ala M.HhaI C5-Cytosine DNA methyltransferase with unmodified DNA and AdoHcy'''<br />
{{Structure
|PDB= 2z6q |SIZE=350|CAPTION= <scene name='initialview01'>2z6q</scene>, resolution 2.79&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DCZ:2'-DEOXYCYTIDINE'>DCZ</scene> and <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37]
|GENE= hhaIM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=735 Haemophilus parahaemolyticus])
}}
 
'''Ternary structure of Arg165Ala M.HhaI C5-Cytosine DNA methyltransferase with unmodified DNA and AdoHcy'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Z6Q is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_parahaemolyticus Haemophilus parahaemolyticus] with <scene name='pdbligand=DCZ:'>DCZ</scene> and <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6Q OCA].  
2Z6Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_parahaemolyticus Haemophilus parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6Q OCA].  


==Reference==
==Reference==
The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI., Shieh FK, Youngblood B, Reich NO, J Mol Biol. 2006 Sep 22;362(3):516-27. Epub 2006 Jul 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16926025 16926025]
The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI., Shieh FK, Youngblood B, Reich NO, J Mol Biol. 2006 Sep 22;362(3):516-27. Epub 2006 Jul 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16926025 16926025]
[[Category: DNA (cytosine-5-)-methyltransferase]]
[[Category: DNA (cytosine-5-)-methyltransferase]]
[[Category: Haemophilus parahaemolyticus]]
[[Category: Haemophilus parahaemolyticus]]
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[[Category: transferase/dna complex]]
[[Category: transferase/dna complex]]


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